Rise of drug-resistant superbugs could make Covid pandemic look ‘minor’, expert warns

The Covid-19 pandemic will “look minor” compared with what humanity faces from the growing number of superbugs resistant to current drugs, Prof Dame Sally Davies, England’s former chief medical officer, has warned.

Davies, who is now the UK’s special envoy on antimicrobial resistance (AMR), lost her goddaughter two years ago to an infection that could not be treated.

 

She paints a bleak picture of what could happen if the world fails to tackle the problem within the next decade, warning that the issue is “more acute” than climate change. Drug-resistant infections already kill at least 1.2 million people a year.

 

“It looks like a lot of people with untreatable infections, and we would have to move to isolating people who were untreatable in order not to infect their families and communities. So it’s a really disastrous picture. It would make some of Covid look minor,” said Davies, who is also the first female master of Trinity College, Cambridge.

AMR means that some infections caused by bacteria, viruses, fungi and parasites can no longer be treated with available medicines. Exposure to drugs allows the bugs to evolve the ability to resist them, and overuse of drugs such as antibiotics accelerates that process.

Widespread resistance would make much of modern medicine too risky, affecting treatments including caesarean sections, cancer interventions and organ transplantation.

 

“If we haven’t made good strides in the next 10 years, then I’m really scared,” Davies said.

 

Without the development of new treatments “it’ll grind on for decades and it won’t burn out. We know that with viruses, they burn out, you generally develop herd immunity, but this isn’t like that.”

 

Last week the UK government announced a national action plan on AMR, with commitments to reduce its use of antimicrobials in both humans and animals, strengthen surveillance of drug resistant infections, and incentivise industry to develop new drugs and vaccines.

 

Launching the plan, Maria Caulfield, the health minister, said: “In a world recovering from the profound impact of the Covid-19 pandemic, international collaboration and preparedness for global health challenges have taken on an unprecedented level of importance.”